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Solid Phase Organic Synthesis by Anthony W. Czarnik,

The rapid expansion of combinatorial chemistry has renewed interest in solid-phase organic synthesis, a method that lends itself well to creating biology chemistry and screening large numbers of lead compounds. Solid-Phase Organic Syntheses, Volume 1 is the first volume in a series that will be updated annually, filling a gap in the existing chemical literature. Providing information previously unavailable from a single resource, this series is dedicated to providing researchers in the field with validated biology chemistry and tested methods for the solid-phase synthesis of interesting biology chemistry and biologically relevant molecules. Solid-phase methods will virtually always be invented for application in combinatorial organic synthesis. To meet these specific needs, Solid-Phase Organic Syntheses, Volume 1 focuses on a single type of synthetic transformation accomplished on solid support, biology chemistry and indicates how procedures are optimized to work with a structurally-wide variety of reagents. Written by recognized leaders in the field who review biology chemistry and test all chemical protocols before publication, organic transformations are organized by type of compound synthesized biology chemistry and reaction type. For the first time, experimental details for proven solid-phase synthetic molecules are collected in a single, invaluable resource. Solid-Phase Organic Syntheses, Volume 1 provides combinatorial chemists biology chemistry and researchers in organic chemistry biology chemistry and medicinal chemistry with the tools biology chemistry and descriptive protocols to achieve syntheses of desired compounds using a variety of solid supports biology chemistry and reagents.
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